A microscopic nervecell analysis theory for elucidating membrane potential dynamics using boundary element method

The recent progress of physiological measurement allows us to observe membrane potential behaviors of extensive regions with higher spatial and temporal resolutions. Accordingly, a new theory has been expected with which we can analyze the spatiotemporal dynamics of the membrane potential with the cell-shape and the spatial distributions of electrical parameters taken into consideration quantitatively. We propose a microscopic analysis theory using the boundary element method. An example of a preliminary numerical calculation is also reported. ( 1999 Elsevier Science B.V. All rights reserved.